第1回 ペイン、新規療法を目指して

化学的手法の利用により臨床へのレースをリードする : カタログダウンロード(英語版PDF)

5月12日(月)〜13日(火)

開会基調講演

Catherine Abbadie, Ph.D., Senior Research Fellow, Merck & Co., Inc.

注目分野1: TRPV

Targeting TRPV1 Receptor Antagonist for Treatment of Pain
Chih-Hung Lance Lee, Ph.D., Senior Group Leader, Abbott Neuroscience

Design & Synthesis of TRPV1 Antagonists
Gurdip Bhalay, Ph.D., Chemistry Project Team Head, Novartis Institutes of BioMedical Research

注目分野2: CB1 & CB2

Identification and Exploration of a Novel Series of Heterocyclic Cannabinoid Receptor Agonists for the Treatment of Pain
Paul D. Ratcliffe, Ph.D., Team Leader, Department of Medicinal Chemistry, Organon Laboratories Ltd, a part of Schering-Plough Corporation

注目分野3: P1、P2X3、P2X7

Purinergic Receptor Antagonists: Novel Treatments for Inflammatory and Neuropathic Pain
David S. Carter, Ph.D., Research Scientist, Roche Palo Alto

注目分野4: カリウム&ナトリウムチャンネル

Potassium and Sodium Channel Modulators Designed to Target Neuropathic Pain
Robert Atkinson, Ph.D., Senior Research Investigator, Medicinal Chemistry, Icagen, Inc.

注目分野5: 炎症性痛覚の療法における新たな機会

Development of Peripheral Kappa Opioid Analgesics: Targeting Pain and Inflammation at its Source
Rob Spencer, Ph.D., Director, Preclinical Development, Cara Therapeutics, Inc.

Design and Pharmacological Properties of a Novel Series of Dithiolethione Compounds as Non-Steroidal Anti-Inflammatory Drugs with Minimal Gastrointestinal Toxicity
Bevyn Jarrott, Professor, Florey Neuroscience Institutes, University of Melbourn

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推奨ショートコース *

5月13日(火)午後 (SC6) 創薬とペインのための動物モデル

This short course will highlight specific steps to building better animal models for drug development in the pain area. The session will begin by addressing the ethical considerations of animal research and a framework for identifying appropriate species and models (e.g. surgical v. irritant, disease specific v. general). You will also learn how to better identify and understand the critical biological, histological and electrophysiological endpoints of your programs. Special attention to the applications of animal research in inflammatory, neuropathic and cancer pain will be given during this session.

* こちらのコースへの出席に際しては別途お申し込みが必要となります。
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