市場調査報告書：無機質超微細孔の吸着剤

NEW APPLICATIONS TO EXPAND
THE MICROPOROUS ADSORBENTS INDUSTRY

The microporous adsorbents industry is a mature industry with a wide variety of products satisfying the requirements of well-established applications. However, the expanded scope and applicability of environmental regulations, along with improving living standards around the world, are stimulating significant increases in demand for these products. In addition to environmental forces, newly-invented, specialized microporous adsorbent products are creating novel market opportunities in the electronics manufacturing and biomedical industry sectors.

According to a soon-to-be-released study from Business Communications Co., Inc. (www.bccresearch.com) RC-180R Inorganic Microporous Adsorbent Materials, the market value for inorganic microporous adsorbents is estimated at nearly $1.78 billion in 2001. This total, which include are comprised of the top five and other types of inorganic microporous adsorbents, is forecast to grow at an AAGR (average annual growth rate) of 3.1% to reach 2.08 billion by 2006.

Water and air purification applications in the environmental pollution control industry consume the majority of GAC (granular activated carbon) production. GAC constitutes nearly one-fifth of the total market size and is projected to grow at an AAGR of 3.8%. Its projected growth rate will be negatively affected by relaxed environmental legislation as well as dumping activity from foreign nations.

Zeolites account for the largest market with nearly 62% of the total market and thus heavily influence overall growth rates. Their applications range from detergent builders to high-end catalyst supports in the chemical and petroleum industry. Overcapacity in low-end zeolites and reduced obsolescence of improved high-end products will limit its average yearly growth rate to 2.5% in the next 5 years.

Silica gel adsorbents and activated alumina are expected to have the highest AAGR of 4.8% each, as they increase from $177 million and $91 million in 2001 to a 2006 value of $224 and $115, respectively. Silica gels are the most common desiccants and drying agents and their growth rate will be fueled by applications in healthcare, building materials, and the high-end paper manufacturing industry. Activated alumina adsorbents make common catalyst support in the chemical processing industry. Their application in chromatographic separation columns is expected to accelerate in the biochemical sector.

Clay usage as adsorbents will grow at a rate of 3.4% to a market size of $52 million in 2006. Clays are often used as adsorbents where purity is not a primary concern. Development of pillared intercalated layered clay may offer a niche commercial opportunity. The adsorbent materials discussed have attained best available technology (BAT) status in many of their prominent applications. Although they have achieved significant penetration in those application segments, innovation activity remains brisk.

Market Value of Adsorbents, through 2006
($ Millions)

	2001	2006	AAGR % 2001-2006
Zeolite	1,100	1,245	2.5
Granular activated carbon	334	402	3.8
Silica gel	177	224	4.8
Active alumni	91	115	4.8
Clays	44	52	3.4
Other	32	37	2.9
Total	1,778	2,075	3.1

Market Value of Adsorbents, through 2006
($ Millions)

INTRODUCTION/SUMMARY .......................XIV

WHERE DESIGNER MATERIALS SAVE LIVES?AND CUT COSTS .......................XIV

DRUG DELIVERY .......................1

ADVANCED DRUG DELIVERY SYSTEMS TO CROSS $27 BILLION BY 2005 .......................1
VASCULAR STENT FEATURES BIOACTIVE COATING .......................3
GROWTH HORMONE GAINS FDA NOD .......................3
PACLIMER MICROSPHERES TARGET OVARIAN CANCER .......................4
SHEFFIELD?S INHALER TREATS MIGRAINES .......................5
INHALE DEVELOPS INSULIN METHOD .......................6
POT PATCH GIVES CONTACT HIGH .......................7
ONCOSEED SUCCESSFULLY TREATS PROSTATE CANCER .......................7
PATCH RELEASES ESTRADIOL/PROGESTIN .......................8
NASAL MORPHINE GIVES QUICK PAIN RELIEF .......................8
FIRMS SEEK NEEDLE-FREE DNA-BASED VACCINES .......................9
DNA POWDER ALLOWS LUNG DELIVERY .......................10
TOPIGLAN REVERSES IMPOTENCE TOPICALLY .......................10
?RITALIN? PATCH GETS ATTENTION DAILY .......................11
ANDROGEL PUMPS UP TESTOSTERONE DEFICIENCY .......................12
FIRMS TEAM TO FIND NASAL VACCINE .......................13
MYLAN ESTRADIOL PATCHES APPROVED .......................14
HARD TABLET DISSOLVES QUICKLY .......................14
ANGIOCOL STARVES TUMORS .......................16
GENE EXPRESSION INCREASED 500-FOLD .......................17
CYTOPORTER CROSSES LIPID BARRIERS .......................18
FIRMS STUDY MICROPOR FOR RECOMBINANT PROTEIN .......................19
IMPLANT MAKES INSERTION EASIER .......................20
MRI ALLOWS CRANIAL VIEW .......................20
POLYMER PLATINATE INCREASES POTENCY .......................21
POLYMER CONTROLS BULK DECOMPOSITION .......................22
VECTOR TARGETS SALMONELLA BACTERIA .......................22
ELECTROTRANSPORT BOOSTS CONTROL .......................23
OLIGOMER TECHNOLOGY WIDENS CR APPLICATIONS .......................24
AEROSOL SHOWS TARGETING PROMISE .......................25
NANOPARTICLES BOOST VACCINE .......................26
SUPERPOROUS HYDROGEL MAY CUT MEDICATION .......................27

NEUROLOGY .......................29

NEUROTREND MONITORS GASES AND TEMPERATURE .......................29
VAGUS NERVE STIMULATED FOR SEVERE DEPRESSION .......................30
SALT TREATED COLLAGEN BOOSTS REGENERATION .......................31
BRAIN STEM CELLS PURIFIED DIRECTLY .......................32
GENE INHIBITS NERVE CELL REGENERATION .......................33
STEEL REPLACES CERVICAL DISCS .......................34

ORTHOPEDIC .......................36

4.5 MM CANNULATED SMARTSCREW RELEASED .......................36
SPINE FUSION STUDY SHOWS 100% SUCCESS .......................36
FAKE BONE HARDENS ENDOTHERMICALLY .......................37
SULZER TESTS SPINAL GROWTH FACTOR .......................38
MONOLITHIC POLYMERS FOR BONE PROSTHESES .......................39
CARTILAGE RECONSTRUCTOR IS BIODEGRADABLE .......................40
IMPLANT ALIGNS SMALL BONE BREAKS .......................40
SYNVISC EFFECTIVE IN ?REAL-WORLD? STUDY .......................41
COLLAGEN IMPLANT REPAIRS MENISCUS .......................42
HEAD SYSTEM BOOSTS HIP DURABILITY .......................43
CARTICEL HOLDS UP FOUR YEARS LATER .......................44
CHRYSALIN HEALS FRACTURES QUICKER .......................46
GENZYME MOVES TOWARD PREFORMED CARTILAGE .......................47
POLYMERS BOOST ARTIFICIAL MUSCLES .......................48
"SMART PLASTIC" GIVES BIONIC LEG MEMORY .......................49
FEDS SEEK BONE ALLOGRAFT INPUT .......................49
METAL MESH SPURS BONE GROWTH .......................50
BUILDING A BETTER CAST .......................51
ONE SIZE FITS ALL .......................52
HYBRID JOINT IMPROVES MOBILITY .......................52

HEMATOLOGY .......................54

SULZER SPINE-TECH LAUNCHES SEALANT .......................54
CATHETER SHIELDS NEEDLETIP .......................54
HEMOLINK SHOWS POSITIVE RESULTS .......................55
FIRMS COLLABORATE ON VIRAL INACTIVATION SYSTEM .......................57
HEMOPURE RESTORES BRAIN OXYGENATION .......................57
OXYGENT ELIMINATES BLOOD TRANSFUSIONS .......................58
HEMOPURE BETTER THAN STANDARD FLUID METHOD .......................59
GERMANS EMBRACE ROUTINE FILTRATION .......................60
PCR TESTING FINDS HEPATITIS B IN PLASMA .......................61
ANALYZER WORKS NONINVASIVELY .......................62
MICROBUBBLES IMPROVE ULTRASONIC IMAGING .......................62
TRIAL BOOSTS BLOOD SUBSTITUTE .......................63
POLYMER BEADS DEVISED FOR BLOOD ANALYSIS .......................64
PLASTIC TUBE ENCLOSES SAMPLES .......................64
COATING IMPROVES VISCOSITY TEST .......................65
EMULSION CUTS DONOR NEED .......................67

IMAGING AGENTS .......................69

U.S. DIAGNOSTIC IMAGING?A GROWING MULTIBILLION MARKET .......................69
COMBIDEX IMPROVES METASTATIC DIAGNOSIS .......................71
TNT TARGETS NECROTIC TUMORS .......................71
MEDLOGIC GLOBAL CORP. STRENGTHENS POSITION .......................72
AGENT IMAGES CELLULAR INJURY .......................73
ANNEXIN-V SUCCESSFUL WITH HEART CELL DEATH .......................73

LEGAL AND REGULATORY .......................75

TARGIS TREATMENT SAFE WITH PELVIC IMPLANTS .......................75
FDA ACCEPTS IMAGENT REVIEW APPLICATION .......................75
NOD FOR CRYOLIFE SURGICAL ADHESIVE .......................76
JAPAN APPROVES NIR W/SOX STENT .......................76
HEMOPURE TRIAL GETS CANADIAN APPROVAL .......................77
SALINE BREAST IMPLANTS GET INITIAL FDA NOD .......................78
BILIARY ENDOPROSTHESIS STENT APPROVED .......................78
BREAST IMPLANT PLAINTIFFS CAN SUE .......................78
GUIDANT TRISTAR CORONARY STENT OK?D .......................79
CATHETER INNOVATIONS AWARDED CE MARK .......................79
EMBOSPHERE MICROSPHERES GAIN AUSSIE APPROVAL .......................80
CANADIAN NOD TO SURGERY SEALANT .......................80
REBAR MICRO CATHETERS APPROVED FOR U.S. .......................81
PEDIATRIC DIAGNOSTIC CATHETERS APPROVED .......................81
BIOMEDICAL RESEARCH FUNDING MAY INCREASE .......................82
ONCE-A-DAY BPH ORAL DRUG OK?D IN EUROPE .......................82
SPECTRANETICS LASER APPROVED .......................83
FDA GIVES COHERENT APPROVABLE LETTER .......................83
FDA TO REVIEW COMBIDEX NDA .......................84
FDA APPROVES ULTRASOUND THERAPY .......................84
FEDS OK TWO SALINE-FILLED IMPLANTS .......................85
FDA GIVES IDE TO DUAL-CHAMBER ICD .......................85
HCFA ALLOWS EARLIER BONE STIMULATOR .......................86
FDA APPROVES LASIK EYE SURGERY .......................86
HECTOROL-R-INJECTION GETS FDA APPROVAL .......................87
CHRONIC WOUND DRESSINGS GET NOD .......................87
FDA APPROVES VISUDYNE FOR AMD .......................89
ANGIOJET APPROVED FOR PERIPHERAL ARTERIES .......................90
FDA APPROVES CUTTING BALLOON .......................91
COURT VACATES TROVAN JURY AWARD .......................91
FDA APPROVES SPINAL CAGE .......................92
ARTERIAL STENT GETS U.S. APPROVAL .......................92
PANEL URGES OK FOR LUNG SEALANT .......................93
FDA CLEARS HYDROGEL DRESSING .......................93
FEDS GIVE NOD TO ARRHYTHMIA TREATMENT .......................93
CAL-TEST DIAGNOSTICS TO STOP MAKING KITS .......................94
JURY RULES IN FAVOR OF BECTON, DICKINSON .......................95
APLIGRAF APPROVED FOR DIABETIC FOOT ULCERS .......................95
MALLINCKRODT WINS LITIGATION COSTS .......................96
FDA APPROVES COHESION SURGICAL HEMOSTATS .......................97
EDWARDS ALLEGES PATENT INFRINGEMENT .......................97
UK APPROVES ALZA DITROPAN XL .......................98
CE MARK GOES TO MEDTRONIC RENAL STENT .......................98
FDA CLEARS FASTPACK TEST .......................99
FDA APPROVES BIOZ.PC SYSTEM .......................100
IMPLANTABLE PUMP FOR LIVER CANCER .......................100
EU BACKS OVARIAN CANCER TREATMENT .......................101
FIBRIN SEALANT APPLICATOR CLEARED .......................102
IMAGING AGENT PASSES MUSTER .......................102
LASER PHOTOLYSIS GETS FDA NOD .......................103
GUIDANT WINS GSI APPEAL .......................104
SMART TRIAL AWAITS DATA REVIEW .......................104
METFORMIN GAINS POSITIVE RESULTS .......................105
CANADA APPROVES STENTLESS VALVE .......................105
VION LAUNCHES FIRST TAPET TEST .......................106
BRISTOL-MYERS ORDERED TO LIST ABI PATENTS .......................106
MICROCATHETERS CLEARED FOR VASCULAR USE .......................107
FEDS OK VIVELLE FOR OSTEOPOROSIS PREVENTION .......................108
INTERPORE GETS CANADIAN NOD FOR AGF PRODUCTS .......................108
FDA APPROVES MOSAIC HEART VALVE .......................109
SMALL DEFIBRILLATORS PASS FDA SCRUTINY .......................110
BRACHYSEED APPROVED FOR PROSTATE CANCER .......................110
BIOMAX TO TEST OPTICAL CATHETER .......................111
DOCTOR SUES MEDTRONIC OVER GRAFT .......................111
BRISTOL-MYERS TO SETTLE PATENT SPAT .......................112
FDA APPROVES CORONARY STENT .......................112
FDA CLEARS BALLOON CATHETER .......................113
ELECTRONIC TESTING NETS ACCREDITATION .......................114
POINT-OF-CARE TEST MAY BE CHOLINESTERASE .......................115
CATHETER GETS FEDERAL CLEARANCE .......................115
ALTUS LASER NETS CE MARK APPROVAL .......................116
OPHTHALMIC LASER CLEARED BY FDA .......................116
FDA GIVES NOD TO MEDTRONIC STENT .......................117
FDA APPROVES IMAGING SYSTEM .......................118
WORLD DIAGNOSTICS INKS AFRICAN HIV TEST DEAL .......................119
MONOCLONAL WINS ORPHAN STATUS .......................119
SILVER NANOCRYSTALS OK FOR CHRONIC WOUNDS .......................120
QUORUM GROUP TO SETTLE LAWSUITS .......................121
CANADIAN FEDS APPROVE BRACHYSEED .......................122
ZOLL DEFIBRILLATOR GETS FDA CLEARANCE .......................122
HYCOR BIOMEDICAL ADDS AUTOIMMUNE LINE .......................123
MICROSPONGE GETS FDA NOD .......................124
FDA NIXES CLEARANCE FOR COMBO PATCH .......................124
FDA APPROVES ULCER BUG TEST .......................125
HEART FAILURE TEST GAINS FDA NOD .......................126
OPTICAL BIOPSY GETS PREMARKET APPROVAL .......................127
GLUCOSE MONITOR APPROVED FOR DIABETES .......................128
FDA CLEARS CARDIO SCREEN .......................129
DURASUL OK FOR KNEE IMPLANTS .......................129
FEDS APPROVE CANCER MAPPING .......................130
GENZYME ACCUSES ATRIUM OF PATENT INFRINGEMENT .......................131
BRIEFLY NOTED .......................132

CORONARY .......................135

ANGINA EASED WITH MPMR .......................135
ABIOMED CREATES SMALLER CANNULA .......................136
IMPLANT SCIENCES STUDIES RADIOACTIVE STENTS .......................136
CATHETER TREATS ATRIAL FIBRILLATION .......................137
PROTEIN DELIVERY FOR CARDIOVASCULAR DISEASE .......................138
MICROPARTICLE DETECTS MYOCARDIAL PERFUSION .......................139
PRIZM DEFIBRILLATION SYSTEM WORLD?S TINIEST .......................140
ALLOGRAFT VALVE ADDED TO TRANSPLANT OPTIONS .......................141
ANNULOFLEX GETS FDA NOD FOR VALVE REPAIR .......................141
RADIOACTIVE SLEEVE MAY PREVENT HYPERPLASIA .......................142
PHOTOLINK COATING MAKES STENT SLIDE .......................142
CARDIOFIX PERICARDIUM HAS PHOTOFIX TECHNOLOGY .......................143
THINNEST CARDIAC PACING LEAD LAUNCHED .......................144
BETA RADIATION REDUCES RESTENOSIS .......................144
GAMMA-2 RADIATION REDUCES BLOCKAGE .......................146
RESYNCHRONIZATION GIVES LONG-TERM BENEFITS .......................147
DEVICE RADIATES FOR TEMPORARY BRACHYTHERAPY .......................149
GUIDING CATHETER PINPOINTS ARRHYTHMIA .......................150
BYPASS GRAFT LASTS 3-YEARS .......................151
SOFT TIP ALLOWS GENTLE ENTRY .......................152
GUIDANT DELIVERS FOURTH VERSION .......................152
MONITOR CHECKS UNEXPLAINED FAINTING .......................154
GOLD COAT MAKES STENT MORE VISIBLE .......................154
MEDTRONIC STARTS HEARTBEAT PRODUCTS .......................155
STUDY TOUTS THROMBOLYSIS ADJUNCT .......................156
DATA SUPPORT GUIDANT ANCURE .......................157
CARDIOTECH STUDIES RADIOACTIVE SLEEVES .......................158
POLYMER CATHETER IS ANTIMICROBIAL .......................158
POLYMER IMPROVES EXPANDABLE SHEATH .......................159
ANGIOPLASTY BALLOON TAKES DIFFERENT SHAPES .......................160
BRAID GIVES CATHETERS FLEX .......................160
SEAL SPORTS COLLAGEN WEAVE .......................161
URETHANE GRAFT TO REPLACE VEIN .......................162

WOUNDS/TISSUE REPLACEMENT .......................163

DRESSING TREATS SKIN INJURIES .......................163
ORTEC TO CULTURE AUTOGRAFT SUBSTITUTES .......................163
GEL STOPS POST OPERATIVE BLEEDING .......................164
SEALANT STOPS HEAVY BLOOD LOSS .......................164
ORTEC?S CCS HEALS STUBBORN ULCERS .......................165
BIOSTEEL GOATS BORN TO MAKE SPIDER SILK .......................166
ADHESIVE TECHNOLOGY IS "LIGHT-SWITCHABLE" .......................167
BIOMATERIAL ENHANCES TISSUE FIXATION .......................167
J&J BANDAGE AIDS HEALING .......................168
BIO-VASCULAR INTRODUCES APEX PROCESSING .......................168
POLYMER AND FOAM PRODUCTS REPAIR SKIN .......................169
ATRISORB GTR BARRIERS CONTAIN DOXYCYCLINE .......................170
PROCYTE FURTHERS CU PEPTIDE TECHNOLOGY .......................171
SQUIBB MAKES ABSORBING FILM .......................171
APLIGRAF GETS A FOOT UP .......................172
NEEDLE INJECTION EXPANDS GELFOAM .......................173
MEDTRONIC INTRODUCES SMALLEST DEFIBRILLATOR .......................174
DERMAGRAFT RESULTS ATTAIN SIGNIFICANCE .......................175
HYDROGEL COATINGS SLIPPERY WHEN WET .......................176
SPONTANEOUS MUTATION YIELDS "IMMORTAL SKIN" .......................177
MATRIX EFFECTIVE IN ULCER STUDIES .......................178
OTHER ITEMS .......................179
BRIEFLY NOTED .......................180

INDUSTRY NEWS .......................181

STERILIZATION PRODUCTS AND SERVICES EXPANDING IN THE COMING YEARS .......................181
EXTEN SNARES FUNDING FOR SYNTHETIC BIO-LIVER .......................183
XCYTE THERAPIES SIGNS BEAD DEAL WITH DYNAL .......................183
ELAN, RIBOZYME FORM JOINT VENTURE .......................184
LIVER DIALYSIS UNIT MARKETING BEGINS .......................185
ENDIUS, CENTRAL MEDICAL ENTER SPINE MARKET .......................185
CYGNUS SELLS DRUG DELIVERY BUSINESS .......................186
NPS PHARMACEUTICALS TO MERGE WITH ALLELIX .......................186
INJEX DISTRIBUTION EXPANDS IN MEXICO .......................187
WRIGHT MEDICAL BUYS CREMASCOLI ORTHO GROUP .......................187
SILZONE-COATED HEART VALVES RECALLED .......................188
THERMO CARDIOSYSTEMS IS UP FOR SALE .......................189
TORAY TO SELL BIONX STENTS IN JAPAN .......................189
MEDI-JECT TO MERGE WITH PERMATEC HOLDING .......................190
ALLIANCE TO MARKET INCONTINENCE PRODUCT .......................190
MEDTRONIC EXPANDS IN SWITZERLAND .......................191
COMPANIES FORM GENZYME BIOSURGERY .......................192
THREE COMPANIES MERGE TO FORM CURIS CO. .......................193
GAMBRO EXPANDS DIALYZER PRODUCTION .......................194
WART REMOVAL PATCH LAUNCHED .......................195
INNOVASIVE DEVICES MERGER COMPLETE .......................195
RAYCHEM, MEMRY INK MARKETING PACT .......................196
COHERENT, HOSPITAL AGREE ON PHOTOMEDICINE STUDY .......................196
AFFINITY MODEL HAS PACEMAKER PROBLEMS .......................196
FRESENIUS MARKETS RENALTECH?S DEVICE .......................197
RADIO ENERGY TREATS CORONARY ARTERY DISEASE .......................198
VALVE IMPROVES CARDIOPUMP CPR .......................198
HUMAN ALLOGRAFT HEART VALVE IMPLANTED .......................199
M.D. PERFORMS VAD IMPLANT SANS STERNOTOMY .......................200
REPEL-CV PASSES CLINICAL TRIAL .......................201
ENDOTHELIALIZING GRAFTS FOR CANINE STUDIES .......................201
BATTERED WOMEN PUT BEST FACE FORWARD .......................202
VASCULAR GRAFT ENTERS GREECE, TURKEY .......................202
VIACORD, T. BREEDERS MERGE TO FORM VIACELL .......................203
MEDLOGIC TO MARKET SKIN PROTECTANT .......................203
ST. JUDE MARKETS DIAGNOSTIC EP CATHETER .......................204
MEDAMICUS EXPANDS HEADQUARTERS, PLANT 45% .......................205
LIFECORE OPENS GERMAN SUBSIDIARY .......................205
PIONEERING SURGEON WINS $500,000 .......................205
BAYER, ALZA FORM SALES ALLIANCE .......................206
GLOBAL E-CARE ADDS ON-LINE MEMBERS .......................207
BAXTER BUYS OXYGENT RIGHTS .......................207
IMAGING COUNCIL FORMED .......................208
FIBRILLATION COMBO HITS EURO MARKET .......................210
SONOTHERAPY SHOWN VIA LIVE TELEVISION .......................211
WORLD HEART ACQUIRES NOVACOR .......................212
ADVANCED TISSUE CEO INVENTOR OF THE YEAR .......................212
ACCENT TO ACQUIRE BIO-RAD ASSETS .......................213
GENZYME BIOSURGERY MERGER PROGRESSES .......................213
CONSORTIUM GOES WITH MALLINCKRODT .......................214
BRISTOL-MYERS, EXELIXIS EXPAND COLLABORATION .......................215
TRIO AGREES TO DEVELOP AGENT .......................216
BAXTER ACQUIRES NA VACCINE .......................216
CELERA, INCYTE OPEN DATABASES .......................217
ABBOTT, EISAI AGREE ON COMPOUND .......................217
PHILIPS MEDICAL GETS CARDIOLOGICA .......................218
CARDIAC SCIENCE BUYS CADENT MEDICAL CORP. .......................218
JOSTRA BUYS BENTLEY UNIT .......................219
CYTOGEN TO ACQUIRE ADVANCED MAGNETICS .......................219
BIOSHIELD TECHNOLOGIES TO ACQUIRE AHT CORP. .......................220
MYRIAD BUYS RIGHTS TO GENZYME PATENT .......................220
AHP TO REDUCE IMMUNEX OWNERSHIP .......................221
DEPUY TO SELL ORTHOLOGIC DEVICE .......................222
FDA APPROVES STEERABLE CATHETER .......................222
B&L EXPECTS LOWER SALES, EARNINGS .......................223
RIGEL, NOVARTIS AGREE TO DISCOVER DRUGS .......................224
INSURANCE FIRMS COVER BONE STIMULATOR .......................225
GENZYME INKS NOVATION CHEST-DRAINAGE DEAL .......................225
NORTH AMERICAN, THESEUS TO MERGE .......................226
BAXTER ALLIES WITH PEPTIDE THERAPEUTICS .......................227
HUDSON TO BUY SHERIDAN TUBE LINE .......................228
ABIOMED BUYS PENN HEART RIGHTS .......................228
CORDIS TO SUPPLY STENTS TO NOVATION .......................229
DOW, EPICYTE DEVELOP MONOCLONALS .......................230
ICN BUYS MEDICAL ALLIANCE .......................230
FIRMS OFFER DENTISTS WEB MANAGEMENT .......................231
ELAN MERGING WITH DURA PHARMACEUTICALS .......................232
GENZYME TO ACQUIRE GELTEX PHARMACEUTICALS .......................232
POINT OF CARE, NOVOLYTIC MERGE .......................233
BIOVAIL CORP. TO BUY DJ PHARMA .......................234
PPGX CONSOLIDATES DEVELOPMENT EFFORT .......................234
TYCO TO BUY INNERDYNE, INC. .......................235
INVERNESS MEDICAL TO ACQUIRE INTEG .......................235
CALCITEK BUYS BONE BUSINESS .......................236
ESPERION ACQUIRES TALARIA THERAPEUTICS .......................237
NOVAVAX TO BUY FIELDING PHARMA .......................237
GENZYME ALLIES WITH CAMBRIDGE .......................238
CAMTRONICS ACQUIRES CARDIOLOGY GROUP .......................239
EPOCH BIOSCIENCES BUYS SYNTHETIC GENETICS .......................240
SENSORMEDICS, PULMONOX SIGN DEVELOPMENT DEAL .......................240
YORK MEDICAL ACQUIRES BIOSTAR NORELIN RIGHTS .......................241
CUBIST, NOVARTIS EXTEND COLLABORATION .......................242
ST. JUDE INKS CONSORTA DEAL .......................243
BRIEFLY NOTED .......................243

OPHTHALMOLOGY .......................250

ARTIFICIAL HUMAN CORNEA GROWN .......................250
SILICON RETINA RESTORES SIGHT .......................250
INTACS TO TREAT KERATOCONUS .......................251
ARTIFICIAL VISION SYSTEM STIMULATES BRAIN .......................252
CLINICS PRODUCE OWN CONCENTRATES .......................253
IONTOPHORESIS DELIVERS MOLECULAR THERAPY .......................254
TORIC CONTACTS FIT FOR ASTIGMATISM .......................255
COMPOSITE LENS GIVES WIDE FIELD .......................256
INTRAOCULAR LENSES SIMPLIFY SURGERY .......................257

RENAL .......................258

ENDOCARE STENT TREATS BPH BLADDER BLOCKAGE .......................258
STAINLESS/TITANIUM UNIT HAS SUBCUTANEOUS ACCESS .......................258
POLYMER DEVICE DETOXIFIES BLOOD .......................260
GAMBROSOL TRIO HANDLES PERITONEAL DIALYSIS .......................260
LOW-DOSE EPO TREATS ANEMIA .......................261
PHD SYSTEM PROVIDES AT-HOME DIALYSIS .......................262
LOW-PROFILE STENT COMBO .......................263

UROLOGY .......................265

INCONTINENCE INSERT SOFT, COMFORTABLE .......................265
IMPLANT STIMULATES URGE, FREQUENCY .......................265
PROTEIN POLYMER GRANTED CORE TECHNOLOGY PATENT .......................266
COMPANIES DEVELOP CONTINENT OSTOMY SYSTEM .......................267
SLING TREATS MALE INCONTINENCE .......................268
COLORECTAL STENT TREATS GROWTHS .......................269
TUMOR MARKER HIGHLY SENSITIVE .......................269
ABDOMINAL PRESSURE CONTROLS INCONTINENCE .......................271
SACRAL NERVE TREATMENT SAFE .......................271
GOLD MAKES TEST ACCURATE .......................272
COATED CATHETERS CUT INFECTIONS .......................273
TOPICAL CREAM LIFTS ERECTILE FUNCTIONS .......................274

BIOMATERIALS .......................276

BINDERLESS POLYURETHANE IS INFECTION-RESISTANT .......................276
TRACKING SYSTEM REFINES GENE THERAPY MEASURES .......................276
NIH PUBLISHES STEM CELL GUIDELINES .......................277
LYMPHOCIDE TESTED ON TOUGH CASES .......................278
MONOCLONAL ANTIBODY SLOWS MICE TUMORS .......................279
COMBINING LIVING, NONLIVING MATERIALS .......................280
ENGINEERED CELLS BOOST SPINE-INJURY MOBILITY .......................281
COMPOUND PUTS HOLD ON ARTHRITIS GENE .......................282

HEPATIC .......................284

BIOARTIFICIAL LIVER SUCCESSFUL IN DOGS .......................284

PULMONARY .......................285

SURFACTANT MAY HAVE AEROSOL FORMULATION .......................285
TECHNOLOGY DESIGNED FOR MOTORLESS INHALERS .......................285
POWDER INHALER USES ENGINEERING RESINS .......................286
BALLOON RESHAPES BRONCHIAL TUBES .......................287

GYNECOLOGY .......................288

MICRO-COIL PROVIDES LASTING CONTRACEPTION .......................288
OVARIAN, BLOOD CANCER RADIOPHARMACEUTICALS .......................289
FDA CLEARS OXYGEN MONITOR .......................290
SAVVY WOMEN ACCEPT STD PREVENTATIVE GEL .......................291

GASTROENTEROLOGY .......................292

GASTRIC STIMULATION SYSTEM RELIEVES NAUSEA .......................292
SEWING UP HEARTBURN SANS INCISION .......................293

ONCOLOGY .......................294

"SUICIDE GENE" SPIKES CANCEROUS TUMORS .......................294
RADIOACTIVE BEADS TREAT LIVER CANCER .......................294

IMPLANT TECHNOLOGY .......................296

IMPRINTED PROTEINS TRIGGER HEALING .......................296

ORTHODONTICS .......................298

FLEXIBLE DENTAL RESIN COMFORTABLE .......................298
SILICON BANDS TOLERATE HEAT, STRESS, CHEMICALS .......................298
DENTAL MATERIALS GO BACK TO NATURE .......................299

CARDIOLOGY .......................301

MEDTRONIC INTRODUCES SMALLEST DEFIBRILLATOR .......................301
RF GENERATOR GIVES REAL-TIME FEEDBACK .......................302
IMMOBILIZER BOOSTS THORACIC PROCEDURES .......................302
ALTERNANS SPOT CONGESTIVE FAILURE .......................303

IMMUNOLOGY .......................305

SYSTEM ADDRESSES LABORATORY ERRORS .......................305
CHEMISTRY IMPROVES FUNGI TESTING .......................305

ENDOCRINOLOGY .......................307

STAINLESS HEAD FOR STERILE TUNNELING .......................307
GLUCOSE MONITOR CHECKS FOR KETONES .......................307
STRIP TAKES PAIN OUT OF TESTING .......................308
PIG CELLS REGULATE GLUCOSE LEVELS .......................309
GOLD PARTICLE ALZHEIMER TEST .......................310

AUDIOLOGY .......................311

DISPOSABLE AID, LARGE MICROPHONE .......................311

DERMATOLOGY .......................312

EXCIMER LASER FOR PSORIASIS AND VITILIGO .......................312

OTOLARYNGOLOGY .......................314

FLUOROPLASTIC MAY REDUCE EAR INFECTION .......................314
SCAVENGERS TREAT, PREVENT DISORDERS .......................314
CREAM SELECTIVELY INHIBITS INFLAMMATION .......................316

LIST OF TABLES

SUMMARY TABLE
U.S. MARKET FOR SELECTED MEDICAL MATERIALS AND DEVICES, THROUGH 2000 .......................XV
1 ADVANCED DRUG DELIVERY SYSTEMS, THROUGH 2005 .......................2
2 U.S. DIAGNOSTIC IMAGING SALES BY MODALITY, 1999-2004 .......................70
3 U.S. MARKET FOR STERILIZATION PRODUCTS AND SERVICES, THROUGH 2004 .......................182

LIST OF FIGURES

SUMMARY FIGURE
U.S. MARKET FOR SELECTED MEDICAL MATERIALS AND DEVICES, 2000 .......................XVI
1 ADVANCED DRUG DELIVERY SYSTEMS, THROUGH 2005 .......................2
2 U.S. DIAGNOSTIC IMAGING SALES BY MODALITY, 1999-2004 .......................70
3 U.S. MARKET FOR STERILIZATION PRODUCTS AND SERVICES, THROUGH 2004 .......................182

無機質超微細孔の吸着剤

Inorganic Microporous Adsorbent Materials

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