Abstract
Despite the popularity of bisphosphonates in treating osteoporosis, there is
room for improvement in terms of drug efficacy and shorter dosage regimens.
Although weekly courses of Fosamax and Actonel have proven effective in managing
osteoporosis, strict posture and fasting guidelines coupled with
gastrointestinal side effects limit patient compliance. In addition, the market
is still in need of more drugs that not only slow the rate of bone loss but also
assist in building bone. Such shortcomings in existing treatments are presenting
growth opportunities to new market entrants. The introduction of bisphosphonates
with monthly and yearly dosing regimens is expected to improve patient
compliance, while new anabolic agents are expected to provide severe sufferers
with better treatment options.
This Frost & Sullivan research examines the U.S. market for non-hormonal
prescription medications used to treat osteoporosis such as bisphosphonates,
selective estrogen receptor modulators (SERMs), calcitonins, and parathyroid
hormones (PTHs). Each segment provides revenue and patient forecasts by drug,
product analysis, and a detailed look at the major issues and factors affecting
market growth.
Increased Awareness Essential to Facilitate Diagnosis and Effective
Treatment
Low awareness and poor understanding of the disease are a major factor behind
the late diagnosis and ineffective treatment for the millions suffering from
osteoporosis. The symptoms behind osteoporosis are not easily recognizable until
multiple fractures have occurred making it all the more difficult for accurate
diagnosis and timely treatment. "Plain X-rays also fail to reveal bone loss
until 20 to 50 percent loss has already occurred," observes the analyst of
this research. "Consequently, less than 10 percent of the estimated 44
million Americans suffering from osteopenia and osteoporosis are diagnosed and
treated." Extensive sales and promotional campaigns should educate patients
regarding the importance of receiving treatment at an early stage and equip
physicians with the tools necessary to quickly and easily identify the symptoms
behind low bone mass.
Anabolic Agents Set to Dramatically Expand Market
Existing antiresorptive therapies are unable to replace lost bone or rebuild
new bone mass, and therefore prove ineffective for patients with severe
osteoporosis and at a very high risk of developing fractures. "Anabolic
agents such as parathyroid hormones (PTHs) are capable of increasing bone
mineral density (BMD), restoring skeletal structure, and curtailing fracture
risk to a greater extent than traditional drugs used for osteoporosis,"
explains the analyst.
At present, Eli Lillys Forteo (teriparatide), which was launched in December
2002, holds the distinction of being the first and only anabolic agent with the
ability to build bone mass. As many other companies follow suit in developing
anabolic agents, the osteoporosis therapeutics market is expected to see a surge
in revenues.
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Table of Contents
1 EXECUTIVE SUMMARY
Executive Summary
2 TOTAL MARKET
Overview
- Scope and Segmentation
- Research Methodology
- Introduction
- Market and Technology Trends
Market Dynamics
- Demand Analysis
- Patient Forecasts
- Revenue Forecasts
- Factors Affecting Market Growth
- Industry Issues and Challenges
Competitive Landscape
- Competitive Structure
- Pipeline Analysis
- Market Share Analysis
Frost & Sullivan Awards
- Product of the Year Award
- Industry Innovation and Advancement of the Year Award
- Product Innovation Award
- Technology Excellence Award
- Entrepreneurial Company of the Year
3 BISPHOSPHONATES MARKET
Overview
- Introduction
- Market Engineering Analysis
- Segment Issues
Market Forecasts and Trends
- Revenue Forecasts
- Patient Forecasts
- Pricing Trends
- Product Analysis
Competitive Analysis
- Competitive Structure
- Market Share Analysis
4 SERMS MARKET
Overview
- Introduction
- Market Engineering Analysis
- Segment Issues
Market Forecasts and Trends
- Revenue Forecasts
- Patient Forecasts
- Pricing Trends
- Product Analysis
Competitive Analysis
- Competitive Structure
- Market Share Analysis
5 CALCITONINS MARKET
Overview
- Introduction
- Market Engineering Analysis
- Segment Issues
Market Forecasts and Trends
- Revenue Forecasts
- Patient Forecasts
- Pricing Trends
- Product Analysis
Competitive Analysis
- Competitive Structure
- Market Share Analysis
6 PARATHYROID HORMONES MARKET
Overview
- Introduction
- Market Engineering Analysis
- Segment Issues
Market Forecasts and Trends
- Revenue Forecasts
- Patient Forecasts
- Pricing Trends
- Product Analysis
Competitive Analysis
- Competitive Structure
- Market Share Analysis
7 APPENDIX
Decision Support Database
- Population 65 and Older
- Female Population
- Obstetricians and Gynecologists
- Medicare Enrollment
- Private Health Insurance
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