Abstract
Multiple sclerosis (MS) is a chronic demyelinating disease of the CNS that
causes significant disability in young adults. Worldwide, millions of people
are affected by multiple sclerosis. Although there is no cure, approved
treatments are available to slow the progression of MS and offer improved
quality of life.
The market for these treatments has grown 15% since 2004 and continued
double-digit growth is expected in the near term. Kalorama Information' s:
Multiple Sclerosis: A Market Briefing takes a detailed look at multiple
sclerois worldwide and the market for MS treatments, as well as treatments
that will be available in the future. Kalorama' s study focusing on the
following four treatments:
- Copaxone
- Avonex
- Rebif
- Betaseron/Betaferon
As part of its continuing coverage, this report provides:
- Overview of Multiple Sclerosis and its Progression.
- Complete Incidence and Prevalence Statistics For U.S. and Worldwide.
- Triggers and Risk Factors of MS.
- Review of Multiple Sclerosis Treatments on the Market
- Market Size and Forecasts For Treatements to 2011.
- Issues and Trendsfacing MS treatment
- New Multiple Sclerosis Treatments in the pipleline.
As part of Kalorama' s trusted information -gathering process, intensive
research into company, trade and medical literature was supplemented by
interviews with experts in the multiple sclerosis treatment industry.
Interviews make up the source of forecast and market size figures.
The Multiple Sclerosis market is examined for the U.S., European and Japanese
markets.
Table of Contents
CHAPTER ONE: EXECUTIVE SUMMARY
- Introduction
- Scope and Methodology
- Size and Growth of the Market
- Issues an Trends Affecting Market
- Leading Competitors
CHAPTER TWO: INTRODUCTION
- Introduction to Multiple Sclerosis
- Progression of Multiple Sclerosis
- Relapsing-remitting MS
- Primary-progressive MS
- Secondary-progressive MS
- Progressive-relapsing MS
- Benign MS
- Pathogenesis of MS
- Inflammatory Response and MS
- Triggers
- Risk Factors
- Physical Complications of MS
- Diagnosing MS
- Demographics and Statistics
CHAPTER THREE: TREATMENTS FOR MULTIPLE SCLEROSIS
- Description of Products
- Copaxone
- Avonex
- Rebif
- Betaferon/Betaseron
- Tysabri
- Novantrone
- Research and Development
- Late Stage Development
- Early to Mid Stage Development
- Phase II Development
- Phase I Development
- Preclinical Development and Research
- Experimental Drugs and Treatments
- Discontinued Development
- Market and Competitive Analysis
- World Market Analysis
- World Competitive Analysis
- Markets by World Region
- U.S. Market
- Europe Market
- Japan Market
CHAPTER FOUR: ISSUES AND TRENDS AFFECTING THE MS MARKET
- Introduction
- Medicare and Health Insurance Issues
- NIH MS Funding Reduction
- Stem Cell Controversy and MS
- Access to Life-Saving Medicine Act and MS
- Par-3 Discovery
- Cyclophilin D Regulation
- Women and MS
- Pregnancy and MS
- Alternative Therapies in MS Treatment
- MS and Diabetes
CHAPTER FIVE: COMPANY PROFILES
- Bayer Schering Pharma AG
- Biogen IDEC
- Novartis AG
- Sanofi-Aventis
- Merck Serono S.A.
- Teva Pharmaceutical Industries Ltd
- APPENDIX: COMPANY NAMES AND ADDRESSES
TABLE OF EXHIBITS
CHAPTER ONE: EXECUTIVE SUMMARY
- Table 1-1: Multiple Sclerosis Cases in Selected Countries.
- Table 1-2: The Worldwide Multiple Sclerosis Market 2004-2011
- Figure 1-1: The Worldwide Multiple Sclerosis Market 2004-2011
CHAPTER TWO: INTRODUCTION
- Table 2-1: Estimated World Prevalence of Multiple Sclerosis by Selected
Countries
- Figure 2-1: Estimated World Prevalence of Multiple Sclerosis by Selected
Countries
- Table 2-2: World Population by Selected Geographical Region, 2006-2050
- Figure 2-2: World Population by Selected Geographical Region, 2006-2050
- Table 2-2: World Population by Selected Countries, 2006
- Figure 2-3: World Population by Selected Countries, 2006
- Table 2-3: Estimated World Population by Age, sex and Geographical Region,
2006
- Figure 2-4: Estimated World Population by Age and Geographical Region, 2006
- Figure 2-5: Estimated World Population by Sex and Geographical Region, 2006
CHAPTER THREE: TREATMENTS FOR MULTIPLE SCLEROSIS
- Table 3-1: Currently Available Multiple Sclerosis
- Treatments (Brand Name, Generic Name, Marketer and Approval Dates)
- Table 3-2: Estimated World Sales for Leading Products, 2004-2006
- Figure 3-1: Estimated World Sales for Leading Products, 2006
- Figure 3-2: Estimated World Sales for Leading Products 2004-2006
- Figure 3-3: Estimated World Sales for Leading Products, 2006
- Table 3-3: Multiple Sclerosis Products in Late Stage Development
- Table 3-4: Multiple Sclerosis Products in Early to Mid-Stage Development
- Table 3-5: The Worldwide Multiple Sclerosis Market 2004-2011
- Figure 3-4: The Worldwide Multiple Sclerosis Market 2004-2011
- Table 3-6: The Worldwide Multiple Sclerosis Market Estimated Revenues and
Market Share of Leading Suppliers 2006
- Figure 3-5: The Worldwide Multiple Sclerosis Market Estimated Market Share
by Leading Suppliers 2001
- Table 3-7: The Worldwide Multiple Sclerosis Market Projected Revenues and
Market Share of Leading Suppliers 2011
- Figure 3-6: The Worldwide Multiple Sclerosis Market Projected Market Share
by Leading Suppliers 2011
- Table 3-8: The Worldwide Multiple Sclerosis Market Estimated Products
Sales by Geographic Region, 2004-2006
- Figure 3-7: The Worldwide Multiple Sclerosis Market Estimated Products
Sales by Geographic Region, 2004-2006
- Figure 3-8: The Worldwide Multiple Sclerosis Market Estimated Products
Sales by Geographic Region, 2004
- Figure 3-9: The Worldwide Multiple Sclerosis Market Estimated Products
Sales by Geographic Region, 2005
- Figure 3-10: The Worldwide Multiple Sclerosis Market Estimated Products
Sales by Geographic Region, 2006
- Table 3-9: The U.S. Multiple Sclerosis Market Estimated Revenues and
Market Share of Leading Suppliers 2006
- Figure 3-13: The U.S. Multiple Sclerosis Market Projected Market Share by
Leading Suppliers 2006
- Table 3-10: The European Multiple Sclerosis Market Estimated Revenues and
Market Share of Leading Suppliers 2006
- Figure 3-14: The European Multiple Sclerosis Market Projected Market Share
by Leading Suppliers 2006
- Table 3-11: The Japanese Multiple Sclerosis Market Estimated Revenues and
Market Share of Leading Suppliers 2006
- Figure 3-15: The Japanese Multiple Sclerosis Market Projected Market Share
by Leading Suppliers 2006
CHAPTER FOUR: ISSUES AND TRENDS AFFECTING THE MS MARKET
- Table 4-1: NIH Funding By Year