バイオ製薬研究開発への生命科学ツール/技術

Abstract

This market research report is about the important market for life science tools & techs that are used for accelerating the research processes and capabilities of biopharmaceutical R&D. This key research information is valuable and offers readers a detailed overview of the size and shape of the life science tools and techs market and what the products can do to facilitate the advancement of pharmaceutical and biotech drug R&D programs.

Significant life science industry information is presented and reviewed. While pharmaceutical industry generated more than $255 billion in 2002, pharma companies are facing many important issues that could be helped by using new life science tools and technologies. A broad range of industry data is analyzed and reveals that pharma companies have seen their R&D costs dramatically increase over the last twenty years, while their product productivity has declined. In addition, many existing and profitable blockbuster drugs will reach patent expiration dates between 2005-2006. This situation will attract competition from generic or other branded drug makers. It shows that there is a clear need driving the desire for more innovation.

For buyers and sellers of life science tools and techs, this report shows that major pharma companies have increasingly become a source of significant strategic alliance opportunities for many of the companies that comprise the US biotechnology industry. Major pharma companies are motivated to become customers and partners of life science tools companies because the many "tools" companies offer technologies that enable them become more productive, reduce bottlenecks and deliver more marketable products, at less cost, and in a shorter time than in the current 10 to 15-year sequential drug development timeline.

Industrialization of pharmaceutical and biotech R&D has begun. These firms are using genomics and proteomics technologies, and other life science tools that can help these companies reach their drug product objectives. The report discusses some of the newest life science tools and tech advancements including nanobiotechnology, rolling circle amplification technology (RCAT), ICAT, RNAi, phage display, yeast 2 hybrid, PROfusion technology, surface plasmon resonance, biochips, protein arrays, separation technologies, 2D PAGE, HPLC, TOF/TOF, drug target discovery and validation tools among others.

This report has found that the life science tools & techs market size in 2002 was about $1.6 billion and is projected to more than double to about $3.5 billion by 2007, growing at a CAGR of 17.7%. While the economy is currently challenging this market, a pickup in growth is expected after 2004. Readers will learn about key business opportunities and the lessons learned from the life science tools and techs companies. This 155-page study uses 34 figures and tables to illustrate the research findings. Participating companies are mapped against multiple technologies to show where they fit in the competitive landscape. Over 27 life science tools & tech companies are profiled, and the report provides insights about the "tools & techs" that these interesting companies offer, including their strategies, funding and so on.

Table of Contents

1.Overview of the Life Science Tools & Technology Market

• The Competitive Marketplace
  • Analytical Instrumentation Companies
  • Genomics Companies
  • Proteomics Companies
  • Bioinformatics Software Companies
  • BioDatabase Companies
  • Drug Discovery Companies
  • Emerging Tools & Technology Companies
  • Reagent and Consumables Companies
• Overview of Life Science Tool & Tech Developments
  • Gene Sequencing Systems
  • Protein Separation Tools
  • Mass Spectrometers (MS)
  • Microarray and Microfluidic Analytical Technologies
  • Emerging Technologies
  • Informatics - IT for Life Science R&D
• Life Science Tool & Tech Applications for R&D
  • Biopharmaceutical Drug Discovery
  • R&D Diagnostic Tools
  • Pharming Applications

2.Factors Driving Life Science Tools & Tech Developments

• The Opportunity to Make Multi-Billion Dollar Revenues
• The Pace of Pharmaceutical Mergers and Acquisitions
  • Rapid Pace of Scientific Advancements
  • Economics of Pharmaceutical R&D
• Drug Discovery R&D
  • Creation of Post-Genomic Era R&D Databases
  • Proteomics R&D Requres New Tools & Techs

3.Strategies for Life Science Tools & Techs for R&D

• Business Models and Intellectual Property
  • Business Models
  • Intellectual Property (IP)
• Commercializing Life Science Tools & Techs.
  • Develop and Out-License Technology
  • Produce and Sell Consumable Products for R&D
  • Produce and Sell Equipment Platforms to R&D Customers
  • Discover or Validate Drug Targets for Drug Discovery
• Strategic Goals
  • Establish Customer Base with Large Pharmas or Biotechs
  • Make Key Alliances or Partnerships
  • Grow the Company to Reach Critical Mass
• Business Development Strategies
  • Traditional Alliance Partnering
  • Become a Technology Roll-up
  • Merge with Another Biotech

4.Market Forecast

• Life Science Tools & Tech R&D Market Size by Segment, 2002~2007

5.Activities of Analytical Instrument Companies

• Affymetrix, Inc.
• Agilent Technologies, Inc. (Life Sciences)
• Cepheid
• Ciphergen Biosystems, Inc.

6.Activities of Bioinformatics Companies

• Accelrys, Inc (Subsidiary of Pharmacopeia Inc.)
• Celera Genomics Corporation
• Gene Logic, Inc.
• Human Genome Sciences, Inc.
• Incyte Corporation
• InforMax, Inc. (Acq. By Invitrogen)
• Spotfire, Inc.

7.Activities of Drug Discovery Tools Companies

• AVIVA Biosciences
• Caliper Technologies Corporation
• Fluidigm Corporation
• GeneMachines, Inc.
• Nanogen, Inc.

8.Activities of Emerging Technology Companies

• BioTrove
• Illumina, Inc.
• Nanostream
• PamGene
• Xeotron Corporation
• Zyomyx, Inc.

9.Activities of Reagent & Consumables Companies

• ACLARA BioSciences, Inc.
• Genicon Sciences Corporation
• Invitrogen Corporation
• Molecular Staging, Inc.
• Phylos, Inc.
• Quantum Dot Corporation

10.Future Directions of Life Science Tools for R&D

• Future Directions
• Review of Recent Trends
  • Recent Developments in Genomics That Impact Life Science Tools
• Indicators of Future Trends
  • Financing Volitility
  • Biotechnology Conferences
  • University Labs at Work
  • Bioinformatics Software.
  • Bioinformatics Databases
  • Emerging Protein Technology
  • Nanobiotechnology Opportunities Emerging

11.Conclusions and New Opportunities

• Factors for Success or Failure
• Highlights of Hot Development Areas of Life Science Tools
• Life Science Tools & Tech Opportunities
  • Industrial Scale Proteomics
  • The Trend Towards Individualized Medicine
• Summary

12.Appendix A: Tech Map of Industry Segments

• Target Identification Genomic Technologies
• Target Identification Protein Technologies
• Protein Chip
• Protein Databases
• Target Validation
• Drug Lead Screening
• Preclinical Development
• Phase I-III Clinical Development & Diagnostics

13.Appendix B. Technology Map Tables - Life Science Tools & Tech Companies

14.Appendix C: Life Science Glossary