標的特定と評価のためのハイコンテントスクリーニング

Abstract

This Frost & Sullivan research service titled High Content Screening for Target Identification and Validation provides an overview of developments in the pharmaceuticals and clinical diagnostics industry, along with key drivers, influencing market factors, challenges, and analysis of trends recently witnessed. This research service thoroughly examines the drug discovery and therapeutics applications.

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Frost & Sullivan Growth Partnership Service

Based on extensive and in-depth research, real-world consulting work, and new theories tested in hundreds of companies across many industries, Frost & Sullivan has evolved its Growth Partnership Services (GPS) program that provides established and emerging firms with powerful growth visions. Moving beyond token mission statements, GPS provides an actionable vision to growth consulting partners by illustrating how key intelligence and strategic research based on defined goals can guide day-to-day behavior and overall company direction. The foundation of Frost & Sullivan's GPS includes:

• Assisting companies to reach their full potential in the core business
• Providing growth strategies to help companies expand into related businesses
• Preemptively redefining the core business during market turbulence
• Applying the Frost & Sullivan framework to identify and address common mistakes resulting from misaligned corporate strategies
• Recommending growth management strategies through continuous partnership

To maximize the potential for growth within a firm's internal and external environment, Frost & Sullivan consultants can facilitate the creation of strategic programs that deliver improved market success. Frost & Sullivan's strengths lie in combining strategic understanding with market expertise and applying these with absolute commitment to its clients' growth.

Table of Contents

1 | EXECUTIVE SUMMARY

• Scope and Methodology
  • 1. Scope
  • 2. Methodology
• Key Findings
  • 1. Introduction
  • 2. Noteworthy Emerging Technologies and Applications
  • 3. Assessment of Competing Technologies

2 | TECHNOLOGY AND APPLICATIONS VIEWPOINT

• Technology and Applications Analysis
  • 1. Technology Primer
  • 2. High Content Screening Vs. Competing Technologies
• Technological Developments and Innovations in Companies
  • 1. cellWorx High Content Screening Analysis System developed by Applied Precision--USA
  • 2. Microarray Platform developed by Metrigenics--USA
  • 3. Acumen Explorer 488 developed by TTP LabTech--USA
  • 4. Redistribution Technology by BioImage
• Technology Adoption Factor
  • 1. Analysis of Technology Drivers
  • 2. Analysis of Technology Challenges
  • 3. Analysis of Technology Restraints
• Future Trends; Capital Funding; Partnerships and Alliances
  • 1. Technology and Application Trends
  • 2. Capital Funding Analysis
  • 3. Partnerships and Alliances

3 | ASSESSMENT OF INNOVATIONS AND OPPORTUNITIES- USA

• Technological Developments and Innovations in Universities
  • 1. High-Throughput Screening of Neuraminidase Inhibitors--USA
  • 2. A Small Molecule that Induces Mitotic Arrest--USA

4 | ASSESSMENT OF INNOVATIONS AND OPPORTUNITIES- EUROPE AND ASIA PACIFIC

• Technological Developments and Innovations in Companies
  • 1. Multicolor Color BiFC Assays Developed by Purdue University--USA
  • 2. Electrochemical High-Content Screening of Nitric Oxide Release from Endothelial Cells--USA
  • 3. Cellenger- A High Content Screening Instrument developed by Definiens--Germany
  • 4. High-Content Screening Microscopy Identifies Novel Proteins--Germany
  • 5. Pathfinder Technology developed by IMSTAR
  • 6. Bionas Analyzing System
• Technological Developments and Innovations in Universities
  • 1. A High-throughput screening of Genes Encoding Proteins--Tokyo
  • 2. High-Content Screening Using a Human Kinase siRNA Library--Germany

5 | KEY PATENTS; CONTACTS; GLOSSARY

• Key Patents
  • 1. US Patents; 2006
  • 2. US Patents; 2005
• Contacts and Glossary
  • 1. Database of Key industry Participants
  • 2. University Participants
  • 3. Glossary

6 | FROST & SULLIVAN 2006 SCIENCE AND TECHNOLOGY AWARDS

• Product Innovation Award
  • 1. Award Description
  • 2. Award Recipient
• Technology Innovation Award
  • 1. Award Description
  • 2. Award Recipient
• Excellence in Technology
  • 1. Award Description
  • 2. Award Recipient

7 | DECISION SUPPORT DATABASE

• Database Tables
  • 1. Total Healthcare Expenditure (1999-2006)
  • 2. Pharma R&D Expenditure (1999-2006)
  • 3. Govt Biotech R&D Investment (1999-2006)
  • 4. Private Biotech R&D Investment (1999-2006)