遺伝子治療動向：業界への影響

Abstract

This research service discusses global advances in the field of gene therapy.

Table of Contents

1 EXECUTIVE SUMMARY

• Scope and Methodology
  • Scope
  • Methodology
• Introduction and History of Gene Therapy
  • Introduction
  • History of Gene Therapy

2 TECHNOLOGY AND APPLICATIONS VIEWPOINT

• Technology Primer
  • Gene delivery--Vectors; Vehicles; Chemical and Physical Methods
  • DNA Vaccines
  • Additional Approaches
• Applications Analysis and Trends
  • Targets Closest to Market
  • Ocular Disorders--Macular Degeneration And Retinopathy
  • Diabetes
  • Cystic Fibrosis
  • Rheumatoid Arthritis
  • Types of Disorders
  • Coronary Artery Disease
  • Peripheral Artery Disease
  • Cancer
  • DNA Vaccines
• Assessment of Stakeholder Innovation and Technology Transfer Opportunities--Influential Market Factors
  • Mergers and Acquisitions Analysis
  • Regulatory and Political Factors; Industry Trends

3 TECHNOLOGY ADOPTION FACTOR ANALYSIS

• Regulatory Hurdles
  • Safety Issues and Regulatory Barriers
  • Clinical Trials
• Technology or Product Development Restraints and Competing Technologies
  • Technical Barriers
  • Lack of Investor Confidence
  • Gene Patents; Cost and Other Barriers
  • Stem Cells and Other Cellular Therapies
• Analysis of Drivers
  • Analysis of Funding Sources
  • Features and Benefits of Gene Therapy
  • Adoption Drivers for Gene Therapy

4 ASSESSMENT OF INNOVATIONS AND OPPORTUNITIES

• Innovative Developments in North America--Gene Therapy
  • Targeting Cancer Cells with Antibody/Gene/Liposome Nanocomplex
  • Polymer Delivers IL-12 Gene Therapy for Cancer
  • Gene Therapy Promotes Blood Vessel Growth in Peripheral Artery Disease
  • Lentiviral Vectors in Development
  • p53 Gene Therapy for Esophageal Cancer
  • Collagen Used as Target for Cancer Gene Therapy
  • Nanotechnology Gene Therapy for Prostate Cancer
  • Microbubbles Release Therapeutic Genes with Ultrasound
  • Autoantigen-Plasmid Drug Promising against MS
  • Zinc-Finger Protein Agent for Diabetic Neuropathy
  • Gene Therapy for Epilepsy and Parkinson' s Disease
  • Gene Therapy for Osteoarthritis
  • Naked DNA for Cancer Gene Therapy
  • Bare Metal Stents Deliver Gene Therapy to Treat Heart Disease
  • Gene Immunotherapy--T Cells Transformed into Tumor Fighting Cells
  • Emphysema Gene Therapy
  • Hedgehog Agonist Gene for Diabetic Wound Healing
  • Nanoparticles for DNA Delivery
  • FGF Gene Therapy for Myocardial Ischemia
  • Neurturin Gene Therapy for Parkinson' s Disease in Phase II Trials
  • Light-Activated Gene Therapy Targets Knee Injuries; Other Tissue Repair
  • New Lipid Molecule Holds Promise for Gene Therapy
  • Additional Companies
• Innovative Developments in North America--DNA Vaccines
  • Flu DNA Vaccine Candidate Delivered via Needle-Free Injection
  • DOGS Cation Compound Enhances DNA Vaccines
  • Short ISS DNA Sequences Stimulate Immune Responses
  • Cell-Free Production of DNA for Flu Vaccine
  • DNA Bird Flu Vaccine Protects Lab Animals
  • DNA West Nile Vaccine Triggers Immune Response in Human Subjects
  • HIV Vaccines
  • Leukemia Vaccine Uses Tumor Cells Transfected with GM-CSF Gene
  • Adenoviral TB Vaccine
  • Clinical Trial for Ebola Vaccine
• Innovative Developments in Europe--Gene Therapy
  • Gene Therapy for Critical Limb Ischemia
  • Interferon Vector for Cutaneous Lymphoma
  • Belgian and Dutch Companies Seek Spinal Gene Therapies
  • Gene Therapy Appears to Cure Myeloid Disease in Human Subjects
  • Additional Companies
• Innovative Developments in Europe--DNA Vaccines
  • Adoptive Cell Therapy for Melanoma Vaccine
  • E6 and E7 Genes in HPV Vaccine Clinical Trials
  • Vaccine for Kidney Cancer
  • HIV Vaccines
• Innovative Developments in the Asia Pacific Region
  • Gendicine p53 Gene Therapy Follow-up
  • Gene Therapy Successfully Treats Hemophilia
  • Hepatocyte Growth Factor for Liver and Circulatory Disorders
  • DNA Ointment for Atopic Dermatitis

5 PATENTS AND DATABASE OF KEY INDUSTRY PARTICIPANTS

• Patents
  • Key Patents (2005)
  • Key Patents (2006)
• Database of Key Industry Participants
  • Corporate Sector
  • Laboratories and Universities

6 DECISION SUPPORT DATABASE

• Database Tables
  • Total Healthcare Expenditure--World (2002 to 2012)
  • Government Healthcare Expenditure--World (2002 to 2012)
  • Private Healthcare Expenditure--World (2002 to 2012)