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Abstract

This Frost & Sullivan research service titled Advances in Biomarkers provides an overview of emerging technologies and their applications in disease diagnosis, drug discovery and development, personalized medicine etc., along with key drivers, restraints and analysis of trends witnessed in the biomarker industry. In this research, Frost & Sullivan' s expert analysts thoroughly examine the following technologies: genomics, proteomics, metabolomics, and systems biology.

Table of Contents

1 EXECUTIVE SUMMARY

• Scope and Methodology
  • Scope and Segmentation of the Research Service
  • Research Methodology
• Overview of Biomarkers
  • Introduction to Biomarkers
  • Applications of Biomarkers
  • Technology Platform for Biomarker Discovery

2 ASSESSMENT OF ENABLING TECHNOLOGIES FOR BIOMARKER DETECTION

• Noteworthy Innovations in Companies and Universities
  • MASStermind Approach for Biomarker Discovery and Validation
  • Reverse-Capture Autoantibody Microarray Platform for Profiling Prostate Cancer Biomarkers
  • Differential Methylation Hybridization Platform for Drug Response Prediction
  • Protein Detection Made Easy with a New Microchip System
  • Software Solution for Analysis of Microarray Expression and ArrayCGH Experiments
  • Research Grade Mass Spectrometer for Biomarker Recognition
  • Microfluidics-On-Chip Synthesis Platform for Biomarker Discovery
  • Bioinformatics Solution for 2D Image Analysis
  • Isobaric Mass Tags To Heighten MS Performance
  • Bioinformatics Database as a Repository of Biomarkers
  • Imaging Science and Biomarker Development at ISBE
  • Competitive Template PCR with a Twist
  • Chip-Based Technology for Detecting Biomarkers
  • Peptidomics In Biomarker Discovery
• Drivers and Challenges
  • Drivers
  • Challenges

3 ASSESSMENT OF BIOMARKER APPLICATIONS

• Noteworthy Innovations in Companies and Universities
  • Biomarker-Based Test for Detection of Tuberculosis--Australia
  • Proteomics Technology Platform for Target Identification and Predictive Medicine
  • Identification of Plasma Biomarkers for Statin-Induced Myopathy
  • Water Diffusion-Based Biomarker for Breast Cancer
  • Non-Invasive Method to Assess Human Embryo Viability Using Metabolomic Profiling
  • Protein Biomarkers Detected for Ischaemic Liver Injury
  • DNA Methylation Technology for Diagnostic and Prognostic Tests
  • SmartAssays for Early Detection of Damage to Kidney Liver or Pancreas
  • CLIA-Approved Test to Predict Breast Cancer Recurrence
  • Biomarker Development for Traumatic Brain Injury
  • Power3' s Foray into Biomarker Discovery and Development
  • FDA-Approved Prognostic Test For Breast Cancer
  • Biomarker to Detect Cardiovascular Disease at an Early Stage
• Drivers And Challenges
  • Drivers
  • Challenges

4 TECHNOLOGY ADOPTION FACTOR ANALYSIS

• Competitive Landscape
  • Key Findings in the Biomarker Industry
  • Geographic Trend Analysis
• Industry Insights
  • Biomarker Analysis by Therapeutic Areas
  • Analysis of Biomarkers in Clinical Trials
  • SWOT Analysis

5 PATENTS AND DATABASE OF KEY INDUSTRY PARTICIPANTS

• Patents
  • Industry Patents
  • Academic Patents
• Key Participants
  • Companies
  • Universities

6 DECISION SUPPORT DATABASE

• Database Tables
  • Global R&D Expenditure for Biotechnology (2002-2012)
  • Percent Government R&D Investment in Biotechnology (2002-2012)
  • Global Pharmaceutical R&D Expenditure (2002-2012)
  • Global Percentage Pharmaceutical R&D Expenditure (2002-2012)